Ben Roethlisberger led the Pittsburgh Steelers to a narrow win and the Dallas Cowboys overcame the Atlanta Falcons on a day of NFL thrillers.
Fans who enjoy last-minute finishes had to be thrilled on Sunday, as almost every game was decided inside the two-minute warning, several as time expired.
Roethlisberger's one-yard touchdown run with five seconds remaining capped a 20-point rally as the Steelers beat the Jaguars in Jacksonville 20-16.
In Atlanta, Matt Ryan hit Julio Jones with a 34-yard TD strike to tie the game with one minute, 52 seconds remaining. But the Cowboys drove 51 yards in 10 plays to set up Brett Maher with the game-winning, 42-yard field goal as time expired in a 22-19 win.
Redskins kicker Dustin Hopkins had his shot at a last-second game winner, but he missed from 63 yards as the Texans held on 23-21.
The Panthers scored a touchdown with just over a minute remaining against the Lions, but rather than attempt the PAT to tie the game, opted to go for a two-point conversion. The attempt failed and Detroit won 20-19.
The craziness continued in the later games. Denver upset the Chargers 23-22 on a 34-yard field goal by Brandon McManus as time ran out.
And Oakland's Daniel Carlson kicked a 35-yard game winner as the clock hit zero to help the Raiders beat the Cardinals 23-21.
Redskins quarterback Alex Smith suffered a broken tibia and fibula against the Texans and will undergo surgery, according to coach Jay Gruden.
Detroit running back Kerryon Johnson left in the third quarter with a left knee injury and did not return.
Titans quarterback Marcus Mariota left Sunday's game against the Colts just before half-time with an elbow injury and did not return. He was replaced by Blaine Gabbert.
Both Texans guards, RG Zach Fulton and LG Senio Kelemete, went out with injuries in the first half.
Jacksonville right guard A.J. Cann left the game with a hamstring injury.
Raiders receiver Brandon LaFell left the game with an Achilles tendon injury.
Eagles center Jason Kelce left the game in the first quarter with an elbow injury.
Chargers DT Corey Liuget was carted off the field with a knee injury.
By the numbers
Saquon Barkley made history as he became the first Giants rookie with a rushing and receiving score in the same game in nearly four decades.
Andrew Luck reached 160 passing touchdowns on Sunday against the Titans, tying Aaron Rodgers for the second-most passing scores through a player's first 80 career games.
Roethlisberger's game-winning drive against the Jaguars was the 41st of his career in the fourth quarter or overtime, putting him ahead of John Elway for sixth-most by any QB since the NFL-AFL merger.
Panthers coach Ron Rivera, on his decision to go for a two-point conversion late in the loss to the Lions instead of kicking a PAT to tie the game. "I was going for the win. That's just the bottom line."
Roethlisberger, after calling his own number and barely scoring on a one-yard touchdown to beat the Jaguars late: "I don't know what option I am, but it's way down the list. You just find a way."
Buccaneers wide receiver DeSean Jackson, after a loss to the Giants, said his team need more heart: "I feel like a lot of guys on this team fight, put their best foot forward. But we've just gotta have more guys out there, I guess, with heart. We can't keep being the team on the other side of the ball that's always losing."
Week 11 NFL scores
Seattle Seahawks 27, Green Bay Packers 24
Indianapolis Colts 38, Tennessee Titans 10
New York Giants 38, Tampa Bay Buccaneers 35
Pittsburgh Steelers 20, Jacksonville Jaguars 16
Detroit Lions 20, Carolina Panthers 19
Dallas Cowboys 22, Atlanta Falcons 19
Baltimore Ravens 24, Cincinnati Bengals 21
Houston Texans 23, Washington Redskins 21
Oakland Raiders 23, Arizona Cardinals 21
Denver Broncos 23, Los Angeles Chargers 22
New Orleans Saints 48, Philadelphia Eagles 7
Chicago Bears 25, Minnesota Vikings 20
|Ronaldo right about Juventus team spirit – Allegri|
|Klopp: I´m not the pope of football tactics|
|Stade beat Ospreys on emotional Chauvin tribute night|
|Ligue 1 survival bid a marathon not a sprint for Monaco, as club appoints distance runner|
|Vertonghen eyeing Spurs future beyond 2020|
|De Bruyne injuries could be a blessing for City, says Guardiola|
|Emery prepared to face Arsenal´s centre-back crisis|
|Ulster complete Scarlets double, Exeter gain Gloucester revenge|
|Sheffield United 1 West Brom 2: Baggies comeback boosts automatic promotion push|
|Del Potro back on court following knee injury|
|Canelo v Fielding: Rocky ready to write his own fairytale in New York|
|Boca part company with Schelotto after Copa Libertadores loss to River|
|Canelo v Fielding: Tale of the tape|
|Juventus defender Cancelo has knee surgery|
|Canelo v Fielding: Alvarez and Rocky make weight in New York|
|Spalletti does not fear another mid-season crisis at Inter|
|Salah headlines CAF Player of the Year shortlist as Koulibaly misses out|
|Beckham Jr. out of Titans clash|
|Lipsky hits the front at Leopard Creek|
|Pederson coy over Wentz back injury|
|Liverpool ´not really likely´ to be active in January window, reveals Klopp|
|Always on the move and unpredictable - Pavard reveals surprising choice over toughest opponent|
|We need to get back to respect - Lampard alarmed by hate in football|
|Giles returns to England to replace Strauss as director|
|Hansen has no issue with Milner-Skudder Toulon switch|
|Juventus to rest Ronaldo after Torino showdown|
|Titmus strikes gold again as world records tumble in Hangzhou|
|Malinga to captain Sri Lanka in New Zealand|
|Rivaldo would like ´excellent´ Isco at Barcelona|
|United a long way from Mourinho´s vision|
|´Klopp denies an answer!´ - Liverpool boss dismisses questions about ´world-class´ Pogba|
|Returning Nowitzki ´so tired´ after making NBA history|
|Aguero and De Bruyne in contention for Manchester City v Everton|
|Simeone has no plans to cash in on Costa|
|Canelo v Fielding: Alvarez´s greatest nights|
|Fabregas: Chelsea being unfairly scapegoated over racism allegations|
|Crisis? What crisis? Klopp focuses on defensive solutions for United clash|
|Hope cannot inspire Windies as Bangladesh cruise to series win|
|Benitez picks up Premier League Manager of the Month award|
|Chavez, Marquez and Canelo - Mexico´s greatest multi-weight world champions|
|Bale set to miss Real Madrid v Rayo Vallecano|
|Robben out until January as Bayern look to avoid serious injury|
|Milan avoid UEFA ban in FFP punishments.|
|Mourinho compares Liverpool to ´an amazing house´ but insists trophies matter|
|Brisbane Roar 2 Melbourne Victory 4: Muscat´s men hit A-League summit|
|Bumrah confident second Test is ´in the balance´ after India recovery|
|Isco gesture was for a corner or foul, claims Solari|
|Harris leads Australia into ascendancy on day one|
|ATP announces candidates to host future Finals|
|Ronaldo: Juventus fans refuse to lose to Torino|
|Hero Rivers feared he had cost Chargers in KC|
|Williams would welcome Llorente back to Athletic Bilbao|
|Liverpool v Manchester United: Minding the gap|
|Milan elimination unjust, fumes Leonardo|
|Paul hails ´sick´ Harden after record-breaking display|
|Liverpool v Manchester United: Salah, Mane and Firmino v Rashford, Martial and Lukaku in Opta number|
|Canelo open to GGG trilogy as he chases place in Mexican history|
|The big Friday Premier League quiz|
|Harden posts record fourth 50-point triple-double in win over Lakers|
|Barcelona squad happy with Dembele, says Alba|
|Chargers rally past Chiefs to clinch playoff spot|
|WATCH: Chargers top Chiefs on dramatic two-point conversion in final seconds|
|Suns owner Sarver committed to keeping team in Phoenix|
|Chargers WR Allen leaves with injury after near-spectacular catch|
|Socceroos not giving up on Mooy for Asian Cup|
|Cooper says Raiders owner wanted to trade him to Cowboys|
|Pochettino jokes Levy is ´worried´ about losing him|
|Barcelona would welcome Morata – Alba|
|Toure not a priority for West Ham – Pellegrini|
|Koscielny no certainty to face Southampton, says Emery|