Isco offered a timely reminder of his quality to head coach Santiago Solari with a brace in Real Madrid's processional 6-1 win over Melilla in the Copa del Rey.
It meant a 10-1 aggregate triumph over their third-tier opponents to progress to the last 16, with Marco Asensio's quickfire double after the half-hour getting Madrid up and running.
Asensio then crafted a maiden senior strike for rookie centre-back Javi Sanchez, with Isco – making his first start under Solari – netting brilliantly in the 47th minute.
Vinicius Junior got in on the act and Isco's second came after Yacine Qasmi converted a consolation penalty for the visitors.
Mohamed Mohamed Mahanan needed a brilliant last-ditch challenge to deny Mariano as Madrid predictably started quickly and Vinicius blazed over following clever work from Isco.
It left Asensio to show his team-mates how it should be done as he eased through an already-tiring defence in the 33rd minute and caressed a finish past Pedro Luis.
Right-back Pepe Lopez was beaten far too easily by Vinicius, as he set up a second for Asensio, who then turned provider with a chipped pass for Javi Sanchez to volley in off the underside of the crossbar.
Isco spectacularly got in on the act early in the second half, clipping a brilliant 25-yarder into the top corner – earning Solari's applause as the Bernabeu faithful sung his name.
There was less to shout about for Vinicius, who rounded Pedro Luis but could only bundle a finish into the side netting before the goalkeeper repelled a later strike with his feet.
Persistence paid off for the 18-year-old, who unfurled a celebratory jig in the 75th minute after beating Pedro Luis at the second attempt.
Javi Sanchez blotted his afternoon with the foul that allowed Qasmi to send Keylor Navas the wrong way before Isco was given space to lash into the bottom corner from 10 yards in the 83rd minute.
What does it mean? Isco still a Bernabeu favourite
It has been a testing few weeks for one of the most gifted players in Spain. Handed the captain's armband for his return to the starting XI, a week on from being dropped from Solari's squad to face Roma in the Champions League, Isco's first stepovers brought cheers from the Madrid faithful. He had them in the palm of his hand thereafter, albeit against limited opposition.
Asensio brings a clinical edge
If you were to list Real Madrid personalities for whom this season has not quite gone to plan, Asensio would not be near the top. However, one goal from 14 LaLiga appearances is a suboptimal return for such a lavishly-gifted attacker. Scoring two and creating another here might be the spark he needs.
Vinicius dogged but wasteful
A goal and an assist on his first start at the Santiago Bernabeu is not a shabby return for Vinicius, but he might rue the wayward finishing he produced before finally getting on the scoresheet. A hat-trick or more might have pushed him closer to LaLiga starts for a Madrid team lacking a clinical edge this term.
Solari's men travel to Huesca on Sunday, while Melilla continue their Segunda B promotion bid at home to VIllanovense.
|Injury-plagued Nuggets beat Thunder to hold Western Conference lead|
|Southee takes five as Sri Lanka recover in Wellington|
|Kings troll Curry by playing clips of moon landing|
|Guardiola: Premier League title race similar to Barca-Madrid battles|
|Ovechkin joins rare NHL club with second straight hat-trick|
|Liverpool can´t be judged just on trophies – Klopp responds to Mourinho|
|Athletics´ Chapman undergoes procedure on left shoulder|
|Marcelo: Real Madrid miss Ronaldo|
|Ronaldo right about Juventus team spirit – Allegri|
|Klopp: I´m not the pope of football tactics|
|Stade beat Ospreys on emotional Chauvin tribute night|
|Ligue 1 survival bid a marathon not a sprint for Monaco, as club appoints distance runner|
|Vertonghen eyeing Spurs future beyond 2020|
|De Bruyne injuries could be a blessing for City, says Guardiola|
|Emery prepared to face Arsenal´s centre-back crisis|
|Ulster complete Scarlets double, Exeter gain Gloucester revenge|
|Sheffield United 1 West Brom 2: Baggies comeback boosts automatic promotion push|
|Del Potro back on court following knee injury|
|Canelo v Fielding: Rocky ready to write his own fairytale in New York|
|Boca part company with Schelotto after Copa Libertadores loss to River|
|Canelo v Fielding: Tale of the tape|
|Juventus defender Cancelo has knee surgery|
|Canelo v Fielding: Alvarez and Rocky make weight in New York|
|Spalletti does not fear another mid-season crisis at Inter|
|Salah headlines CAF Player of the Year shortlist as Koulibaly misses out|
|Beckham Jr. out of Titans clash|
|Lipsky hits the front at Leopard Creek|
|Pederson coy over Wentz back injury|
|Liverpool ´not really likely´ to be active in January window, reveals Klopp|
|Always on the move and unpredictable - Pavard reveals surprising choice over toughest opponent|
|We need to get back to respect - Lampard alarmed by hate in football|
|Giles returns to England to replace Strauss as director|
|Hansen has no issue with Milner-Skudder Toulon switch|
|Juventus to rest Ronaldo after Torino showdown|
|Titmus strikes gold again as world records tumble in Hangzhou|
|Malinga to captain Sri Lanka in New Zealand|
|Rivaldo would like ´excellent´ Isco at Barcelona|
|United a long way from Mourinho´s vision|
|´Klopp denies an answer!´ - Liverpool boss dismisses questions about ´world-class´ Pogba|
|Returning Nowitzki ´so tired´ after making NBA history|
|Aguero and De Bruyne in contention for Manchester City v Everton|
|Simeone has no plans to cash in on Costa|
|Canelo v Fielding: Alvarez´s greatest nights|
|Fabregas: Chelsea being unfairly scapegoated over racism allegations|
|Crisis? What crisis? Klopp focuses on defensive solutions for United clash|
|Hope cannot inspire Windies as Bangladesh cruise to series win|
|Benitez picks up Premier League Manager of the Month award|
|Chavez, Marquez and Canelo - Mexico´s greatest multi-weight world champions|
|Bale set to miss Real Madrid v Rayo Vallecano|
|Robben out until January as Bayern look to avoid serious injury|
|Milan avoid UEFA ban in FFP punishments.|
|Mourinho compares Liverpool to ´an amazing house´ but insists trophies matter|
|Brisbane Roar 2 Melbourne Victory 4: Muscat´s men hit A-League summit|
|Bumrah confident second Test is ´in the balance´ after India recovery|
|Isco gesture was for a corner or foul, claims Solari|
|Harris leads Australia into ascendancy on day one|
|ATP announces candidates to host future Finals|
|Ronaldo: Juventus fans refuse to lose to Torino|
|Hero Rivers feared he had cost Chargers in KC|
|Williams would welcome Llorente back to Athletic Bilbao|
|Liverpool v Manchester United: Minding the gap|
|Milan elimination unjust, fumes Leonardo|
|Paul hails ´sick´ Harden after record-breaking display|
|Liverpool v Manchester United: Salah, Mane and Firmino v Rashford, Martial and Lukaku in Opta number|
|Canelo open to GGG trilogy as he chases place in Mexican history|
|The big Friday Premier League quiz|
|Harden posts record fourth 50-point triple-double in win over Lakers|
|Barcelona squad happy with Dembele, says Alba|
|Chargers rally past Chiefs to clinch playoff spot|
|WATCH: Chargers top Chiefs on dramatic two-point conversion in final seconds|